Favorite things about epigenetics
Kate is a Ph.D. candidate in the Department of Human Genetics at the University of Chicago, and a member of the Nobrega lab. She was born and raised in Chicago, before leaving to complete her undergraduate degree at the Massachusetts Institute of Technology. After returning to the University of Chicago to join the Department of Human Genetics, Kate joined Marcelo Nobrega’s lab with the goal of extending our knowledge of the role of genetics in complex diseases by exploring the role of splicing in metabolic disorders.
Key Research Outputs
A functional genomics pipeline identifies pleiotropy and cross-tissue effects within obesity-associated GWAS loci. Joslin, A.C., Sobreira, D.R., et al. (2021) Nature Communications 12, 5253.
Extensive pleiotropism and allelic heterogeneity mediate metabolic effects of IRX3 and IRX5. Sobreira, D.R., Joslin, A.C., et al. (2021) Science 372: 6546, 1085-1091.